Tayebeh Dehghan; Amirhossein Asadi; Zahra Sohrabi; Marzieh Akbarzadeh; Kimia Leilami
Abstract
Background: Obesity and non-alcoholic fatty liver disease (NAFLD) are considered as the main causes of liver-associatedmorbidity and mortality. Antioxidant administration was proposed as a remedy for liver problems such as steatohepatitis. This systematic review aimed to examine the effects of supplementation ...
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Background: Obesity and non-alcoholic fatty liver disease (NAFLD) are considered as the main causes of liver-associatedmorbidity and mortality. Antioxidant administration was proposed as a remedy for liver problems such as steatohepatitis. This systematic review aimed to examine the effects of supplementation with various forms of Vitamin E on liver enzymes.Methods: To find relevant articles, in our systematic review article, we searched PubMed, Scopus, Embase, Cochrane library, and Web of Science up to 20 MAY, 2021. Randomized controlled trials (RCTs) on the effects of vitamin E supplementation, in isolation or combined with other nutrients, on liver health were included. After excluding irrelevant records, 21 studies remained.Results: According to the results of the included studies, vitamin E, especially α-Tocopherol or its co-supplementation with other antioxidants, at specific dosage could possibly have positive effects on improving liver functions and levels of Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) enzymes.Conclusion: Vitamin E,could possibly have positive effects on improving the liver function and the levels of ALT and AST enzymes.
Nasrin Nasimi; Mohammad Hossein Dabbaghmanesgh; Mohammad Fararooei; Amirhossein Asadi; Marzieh Akbarzadeh; Zahra Sohrabi
Abstract
Background: Sarcopenia, an age-related decline in muscle mass, strength, and function, contributes to various adverse health outcomes and physical impairments. This study aimed to investigate the association between sarcopenia components and health-related quality of life (HRQoL) among communitydwelling ...
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Background: Sarcopenia, an age-related decline in muscle mass, strength, and function, contributes to various adverse health outcomes and physical impairments. This study aimed to investigate the association between sarcopenia components and health-related quality of life (HRQoL) among communitydwelling older adults.Methods: In this cross-sectional study, 501 adults aged 65 years or older participated. Sarcopenia was diagnosed according to the Asian Working Group for Sarcopenia (AWGS) guideline. Muscle mass was measured by bioelectrical impedance analysis (BIA), muscle strength by hand dynamometer, and physical function by 4-m gait speed. The HRQoL was assessed using 12 item shortform healthy survey (SF-12) questionnaire.Results: There was a significant relationship between the sarcopenia and demographic characteristics (educational levels and smoking habits). After adjustment for age, sex, Body Mass Index, education level, smoking habits, and number of comorbidities, a significant relationship was observed between sarcopenia and physical components of HRQoL. According to multivariate linear regression, low muscle mass was negatively related to physical aspects of HRQoL. Low handgrip strength (HGS) and gait speed (GS) were inversely correlated to both physical and mental components of HRQoL.Conclusion: Our study highlighted the adverse impact of sarcopenia on HRQoL in elderly population. Reduction in muscle strength and physical performance not only affected physical aspects but also were linked with mental components of HRQoL. Therefore, it seems HGS and GS might be good indicators affecting all aspects of HRQoL in the elderly groups.
Fatemeh Moradi; Zahra Sohrabi; Morteza Zare; Najme Hejazi; Marzieh Akbarzadeh
Abstract
Background: Depression is a worldwide disease affecting more than 300 million people and is associated with disability, burden of disease, and significant health care costs. Children’s nutritional status can definitely affect their growth. The burden of malnutrition remains high in developing countries ...
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Background: Depression is a worldwide disease affecting more than 300 million people and is associated with disability, burden of disease, and significant health care costs. Children’s nutritional status can definitely affect their growth. The burden of malnutrition remains high in developing countries and reduces the potential for individual, social, and economic development. The aim of this study was to investigate the relationship between breastfeeding depression and infant’s growth.Methods: This is a cross-sectional study on 90 breastfeeding mothers and their 2-4 month old infants in Yasuj. Data collection in mothers was done by measuring anthropometric variables and by interviews through questionnaires. For assessing maternal depression, Beck Depression Inventory questionnaire was applied, and neonatal physical growth was evaluated by head circumference, weight, and length Z-scores of 2-4 months old infants.Results: The result showed that the relationship between maternal depression score and Z scores of infants’ weight, height, and head circumference was not significant (P>0.05 for all). There were no differences between depression scores of mothers and infants’ growth in different groups of education or occupation among mothers (P>0.05 for all). There was a significant relationship between maternal waist circumference with hip circumference, weight, and number of children (P<0.001 for all).Conclusion: This study showed that depressed mothers, despite having depression, were concerned with the optimal growth of their infants. However, tracking children’s developmental status and maternal depression over the time (especially in depressed mothers or underweight infants) in several stages can be helpful in increasing information in this regard.
